Researchers confirm that the gene which regulates cholesterol exists in the human body
Www.xinhuanet.com Washington Cable of July 7 (reporter takes the post as the navy) Europe studies personnel to announce on the 7th the research results claim, they found the genes of 20 kinds of regulation cholesterol levels in the human body. This not only helps researchers to understand better the human body maintains balanced mechanism of cholesterol, may also help them to develop and treat the new treatment of the relevant disease.
This research is finished by molecular biology lab and Germany Heidelberg university researcher of Europe, research results 7 Japan issued in U.S.A.>On the monthly magazine.
Researchers say, 90% cholesterol exists in cells in the human body, cholesterol in cells will not cause danger to the human body, but the cholesterol content is too high it is the important factor which causes arterioslerosis, coronary artery disease,etc. in the blood. However, cells can adjust the content of cholesterol in the blood through absorbing cholesterol.
Responsible for the gene of this mechanism in confirmation of, researchers isolate some human cells at first, remove cholesterol among them, then observe the whole genome, through the means to change genetic expression way, what genes are observed to react to the change of cholesterol level. Through this kind of method, researchers have confirmed several hundred kinds of suspected genes related to the fact that cholesterol is regulated tentatively first, pass R N one (ribonucleic acid) subsequently Interfere with technology, observe and close different genes to absorb the influence of total amount of cholesterol in cholesterol and cell on cells under the microscope, confirm 20 finally A gene relates to the fact that cholesterol level is regulated.
Researchers say, they, through further studying the concrete mechanism of confirming these genes contribute in cells, and strengthen the clinical trial, is in the hope of finding the target that treats relevant disease to the medicine.
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