Study : The virus will utilize little RNA to inhibit the human immunity seriously or carcinogenic
Recently, British scientist discovers, some virus will utilize little RNA (MicroRNA) Inhibit human body's immunoreactive chance, to implement the attack, cause the emergence of infection even cancer. This discovery makes a new target that little RNA becomes treatment of cancer clicked, contribute to finding the new treatment of preventing and curing cancer.
Little RNA sees more the genome not producing protein in the human body --The so-called one " L The rubbish DNA " China is a kind of minimum encoding RNA, will usually inhibit the expression of the gene. It is estimated, there are 1/3 of the genes that will receive little RNA to adjust and control in the human body. The scientist thinks, little RNA will regulate human body's congenital immune system, but can never verify what kind of consequence this kind of regulation will be produced, it is unable to assert this will relate to the fact that the virus is infected.
London University researcher of institute here one newly>Deliver the thesis, point out, little RNA can inhibit the immunoreaction of the human body from for keeping its adjustment of gene expression at the magazine, but some virus can stimulate little activity of RNA, inhibit the intersection of human body and immunoreactive chance from come, pay, infect with it. It is verified that they study, the card Percy's herpes virus (KSHV, can initiate Percy's malignant tumour of card) Can succeed in accomplishing this . At early stage when the herpes virus is infected with (After infecting 6 hours ) ,The antiviral response of little RNA not merely will strengthen the expression of the virus gene, and will influence interferon to stimulate the expression result of the gene, have promoted the duplication of the virus greatly.
Researchers claim, in the face-off of people and virus, the human immune system will take many ways to prevent or remove the virus to infect, and meanwhile, the virus is evolving constantly, adopt more complicated corresponding tactics to avoid the defence of the immune system. Probably some virus, including being will initiate carcinogenic virus of disease, utilize little RNA to change cells into one that can move in at any time " The virus hotel " ,They are stationed among them, infect the human body.
Director Professor Chris and Boshoff of the cancer research institute of London University institute says, the new discovery shows, little RNA can be clicked as a future therapeutic target, it initiates the carcinogenic new method to infect to help the scientist to find and prevent and cure the virus. (Reporter Liu HaiYing ) (Source : Science and Technology Daily )
|
0 comments:
Post a Comment