Bad reaction of sulfanilamide pyrimidine

Bad reaction of sulfanilamide pyrimidine
Sulfanilamide pyrimidine is that sulfanilamide wide table, middle result restrain the fungus medicine, main bad reaction: The kidney is damaged: Acetylation of product this rate low, product and their acetylation this thing solubility little in urine, it is easy to appear crystallization when the urine is partial and acid, damage the leather cells at the renal tubule and the intersection of other urine and Luis and cause crystalline urine, hematuria, proteinuria, the serious one can cause urine retention or uremia. Blood system: A cell reduces, acute and dissolves courageous and upright anaemia, regenerated obstacle anaemia, blood platelet reducing purpura,etc.. Allergic response: Have rash commonly, urticaria, erythema of exudative much shape, so that the anaphylactic manifestation that peeling dermatitis, big bubble epidermis relaxing, mound bleb and medicine are hot,etc. of nodular erythema, blood vessel edema, only perceptual dermatitis. Before using medicine, should notice whether the patient is the anaphylactic physique, allergic to sulfa drugs, while treating, find drug rash should stop medicines immediately. Digestive system: Disgusting, vomiting, diarrhoea, apocleisis,etc.. Can be seen jaundice, liver splenomegaly occasionally. Neonate, newborn baby in morning can cause jaundice, even present nuclear jaundice. Nervous system: Having a headache, dizzy, tired, tinnitus, ataxia, depression, illusion, fainting from fear, neuritis, losing, spiritual symptom of hearing around,etc.. As to neonate and baby, can also cause abnormal nerve centre grey matter pigmentation, cause the neuron to degenerate and go bad, often cause death. Sulfanilamide medicine can cause Sri Lankan to invite syndrome: Skin and appear large the intersection of water and sore of group at the same time at the mucous membrane, can cause death while being even.

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