Research claims antibacterial pharmaceutical of nanometer can deal with the bacterium and able to bear nature effectively

Research claims antibacterial pharmaceutical of nanometer can deal with the bacterium and able to bear nature effectively
Bacterium it able to bear development of natures to be already very general now, able to bear the intersection of leather and getting blue negative fungus (such as the bacillus of large intestine of medicine especially, bacillus of green suppuration,etc. ) ,It is the bacterium most difficult to deal with in the hospital . China national the intersection of nanometer and the intersection of science and the intersection of centre and the intersection of Chinese Academy of Sciences and the intersection of nanometer and biological effect and safe key the intersection of laboratory and Jiang revitalize Zhao YuYun Dr. and their cooperator, space of seminar, utilize the intersection of nanometer and antibacterial pharmaceutical confront with each other these kind have bacteria able to bear nature under study for action, make progress.
It is low and penetrating that there is the membrane outside negative fungus cells to it is introduced, the leather is blue, and can discharge external arranging the pump system outside of the medicine molecule, it was it that produced important reason able to bear nature. And size, in nanometer of particles, apt to pass through cell membrane, it enters to be like small molecule medicine easy to rank the pump, discharge bacterium behind the cell, and nanometer particle can support high molecule of density, in give play to many price effects interact, with biological member. Utilize these properties of the nanometer particle and develop antibacterial pharmaceutical of new nanometer, perhaps is different from small traditional member's function mechanism against fungus pharmaceutical, it is expected to deal with day by day the serious bacterium is able to bear nature.
Jiang XingYu seminar itself have active pyrimidine the intersection of medicine and the intersection of forebody and little molecule modify on gold the intersection of nanometer and particle, make it reveal fine antibacterial activity. Gold the intersection of nanometer and particle these able to bear medicine to clinical many medicine that separate getting blue leather negative fungus and sensitive fungus of the laboratory standard have good antibacterial results, the resisting that the nanometer particle can have wound the bacterium contributes systematically. Studies have suggested, the nanometer particle destroys the structure of the cell membrane through combining magnesium ion on bacterium's cell membrane, cause the cell content thing to be revealed, bacterium's death. Compared with existing antibiotic, the particle very difficult to induce bacterium produce, able to bear nature nanometer. Meanwhile, nanometer particle take the place of the physiological activity of cells, influence originally people notably.
Relevant experts point out, utilize nanotechnology to activate the small molecule of medicine forebody directly, have widened medicines and screened the range, formate the step after simplifying medicines, has reduced environmental pollution. Such antibacterial tactics have potential medicine using value.
It is reported, this job has got the support of national natural fund committee, Chinese Academy of Sciences and the Ministry of Science and Technology. The relevant result of study was issued and published in the near future >Have. (Reporter Li DaQing )
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