Study the molecular mechanism of finding out drunk response of the brain

Study the molecular mechanism of finding out drunk response of the brain
After special despatch people of June 28 of www.xinhuanet.com San Francisco are drunk, usually feel dizzy and confused, brain seem turn the same, but why appear such a response know to brain. Have found out the concrete molecular mechanism that the brain moves about in the drunk course in a latest research in U.S.A.. Researcher claim this contribute to, develop to alcoholism, the intersection of medicine and get into the habit even new treatment, epilepsy of disease.
The scientific research personnel of Salk Institute for Biological Studies of U.S.A. are a new one>Say, alcohol composition namely ethanol, is thought to change the signal transmission between the nerve cell in the brain on the magazine. Some research showed before this, ethanol will interact with protein of the ionophore directly, but not found out the concrete position of interaction up till now.
The newest finding of Salk Institute for Biological Studies, a certain particular position in a kind of potassium ionophore protein interacts in ethanol and brain. Has know medical research, this kind has been called G I R K's brain when the drug abuse and epilepsy break out of ionophore of potassium and played a key role while moving about.
The latest experiment finds, after ethanol is combined with the particular position in protein, this passway is activated " L Open " ,Nerve cell between " L Signal communication " R Will be weakened, equivalent to produce in the brain " L Short out " .
Researchers say, find out ethanol and activate the concrete position of G my R K passway, will contribute to developing the new treatment which will treat the relevant brain disease. For example, can develop a kind of target to the medicine and make ethanol unable to combine with protein of the passway, to treat alcohol reliance .

|