Wednesday, February 27, 2013

Study and diagnose _ symptom of great significance of liver cirrhosis in early days

Study and diagnose _ symptom of great significance of liver cirrhosis in early days
Attach to a research of third hospital Xie ShiBin,etc. to reveal according to the medical university of Zhongshan, serum is transparent quality it is sour, type before collagen, type collagen can organize fiber not to be made being relatively accurate diagnosis while taking stages different liver, it is transparent for quality sour, type before fiber sensitiveness diagnosed to take is about 80% collagen for liver, and the clinical using value diagnosed to liver cirrhosis with the acid of transparent quality is the greatest.
The liver fiber treats and can slow down or prevent that developing has already become the common understanding to liver cirrhosis in early days. It diagnoses that mainly lies in confirming the fiber intensity of liver. At present, liver live examine, remain, judge, have fiber take objectively comparatively and fiber take reliable method of intensity, but because it has wound nature, not easy to observe dynamically, so difficult to puncture and examine the liver as the regular diagnostic method alive on clinic. It is developed quickly in recent years as not there is not the diagnostic method createdding that serology is diagnosed.
Because clinical diagnosis with consistency of pathological diagnosis difference relatively large, difficult to make accurate diagnosis to early liver cirrhosis at being especially clinical, mostly liver cirrhosis in later period at the time of liver cirrhosis of clinical diagnosis. So, how to depend on measuring fiber index serum to infer or judge the fiber intensity of liver more accurately on clinic, it is a clinical problem that faces at present.
Xie be lasted 253 serum serum qualities transparent, patients of hepatopathy, chronic sour ShiBin,etc. with radiating vaccinating, type before collagen, type levels collagenic, all patients made liver at the same time and organized examining alive. Regard pathological diagnosis as the gold standard, adopt the intersection of ROC and curve, establish the transparent quality of serum sour, type before collagen, type last liver fiber and take collagen and the blocking values of liver cirrhosis and sensitivity, degree, predicted values and predicted values negative positives peculiar that be diagnosed. The research of this experiment shows fiber mark and liver serum and organizes the fiber intensity to have good relevance, organize the stage of fiber development to be identical with the liver. Transparent the intersection of quality and acid the intersection of fiber and sensitiveness diagnosed to take 80% about to liver, to that liver cirrhosis diagnose clinical using value being most large.
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