Bad reaction of the Nitroglycerin

Bad reaction of the Nitroglycerin
Nitroglycerin Nitroglycerin (Nitroglycerol, G! ycerylTrSnnrste) Cardiovascular system Include Nitroglycerin of taking, can happen, pass the intersection of and the intersection of hypoxemia and disease, cause have strange response under the tongue, namely angina pectoris further breaks out to reveal with the electrocardiogram section ST is forced down. The most possible explanation is that the lung artery blood vessel is expanded, lead to the fact some area relative keeping in touch with of lung is low, accompany it as using aminophylline and the different third Epinephrine to shunt with artery hypoxemia disease pulse of functional sound like that, the clinical meaning of this kind of distributary is not still clear, patient and easy to take place patient if old person, hypoxemia of disease to have on nitric acid esters tolerance, it is rational to suffer from to lung illness and depleted patient of the left room and employ the oxygen treatment. Report to after including the Nitroglycerin of melting under 3 example patient's tongues of disease of coronary artery, the serious slow and hypotension aroused in interest happens, the conjecture is the reason that the nervus vagus reflects, it is different kinds of aroused in interest and too slow and appear. Have similar response too after oral nitric acid different mountain pear ester. Include, take behind the Nitroglycerin under the tongue, can take place slight the intersection of blood pressure and drop and having coronary artery convulsion of symptom serious. The report the quiver one of room happens. The Nitroglycerin used in intravenous injection, because the solvent can cause the blood to permeate and press and raise (therefore the cranium is pressed and risen) for third two alcohol , the haemolysis and lactic acid acidosis, this can explain complication of the nervous system. The more serious one is not when the renal function is not complete, can cause solvents to accumulate, but need blood to dialyse and treat. Hematopoietic system Employ the Nitroglycerin excessively and cause methemoglobin blood disease, one employs 100 slices of Nitroglycerin (each slice of 0.4mg) within 36 hours And then, slight cyanosis and 7% of the methemoglobin take place, the patient dies from acute myocardium infarction. Another 1 instil Nitroglycerin (every minute 128 g) while being intravenous while being heavy dose of for a long time ,Have not seen in the blood that there is methemoglobin of pathologic density. Special sense organ According to the experiment of the cat, think nitric acid esters can make the intraocular pressure increase for a long time, because it can't be used in a glaucoma patient. To healthy people, wide angle and narrow angle glaucoma patient quiet note Nitroglycerin or oral nitric acid different mountain pear ester, make the intraocular pressure obviously lower, this kind of intraocular pressure is lowered and had nothing to do with the blood pressure or methemoglobin density all over the body. 1 employ Nitroglycerin stick to, apply pharmaceutical, acerbity and salty sense of taste lose after the 2 week, sense of taste disappear all after the 6 week, and reproducing when resumed after medicines stopped, and then used medicine. Skin 2 employ Nitroglycerin stick to, apply pharmaceutical, take place contact dermatitis, cortex the intersection of steroids and ointment can prevent this kind from react. The intersection of skin and to apply Nitroglycerin produce some erythema and itch rash often, this may be because the pharmacology of the Nitroglycerin acts on. Permanent erythema can develop into bubble rash, papule or edema, should consider for Nitroglycerin or contact allergic response due to the ointment ground substances. The facial skin blood vessel is highly sensitive to function of expansion blood vessel of this kind of medicine, employ nitric acid esters to probably bring out abcchia rosacea. Tolerance and dependence Someone has reviewed tolerance and dependent question about nitric acid esters, when the conclusion can control angina pectoris to break out to employ low dose of nitric acid esters, do not need to administrate heavy dose of treatment continuously for a long time. Decrement can prevent from gradually because the intersection of nitric acid and ester due to dependence harmful parking medicines and reacting.

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