Summary _ mineral of arsenic

Summary _ mineral of arsenic

Brief introduction of arsenic
Arsenic exists in the nature in the form of sulphide mainly, such as Orpimentum (Auripigmentum) and Realgar. The most common compound is the hydride AsH3 or arsine of arsenic. Arsenic exists in the living beings in the state of three prices and five prices
In the body, three price arsenic can be turned into methyl or methyl arsenide in the body.
Discovery of arsenic
In A.D. 250, Magnus of Rome gets arsenic when it is hot altogether by Realgar and soap.
Food source
Fish, marine product, cereal, the intersection of grain and main meal source of arsenic at the valley products.
The supersession is absorbed
Various arsenic are very easy to be absorbed in the meal, can also or breathe and enter body through the skin. Arsenic over 90% in inorganic arsenic aqueous solution of sour salt and inferior arsenic sour salt can be absorbed, multi-form organic the intersection of arsenic and absorption of arsenic its intensity too different, arsine beet beetroot alkali relatively arsine choline large, and the oral hydroxy acetyl is after an arsenic impractical sodium, the majority is discharged by the excrement and urine. The absorption of arsenic sour salt is the transshipment depending on trying the gradient, and the absorption of organic arsenic mainly through the intestines circle but the lipid district spreads. Carry on methyl in the liver after arsenic is absorbed, and receive the influence of internal glutathion, methionine and choline state. Arsenic is discharged by the urine in the form of methyl derivative. In organic arsenic, arsine beet beetroot alkali does not undergo bio-transformation to discharge in the body from urine promptly, and arsine most choline turn the intersection of arsine and beet beetroot into, discharge by the urine behind the alkali, others is similar to choline, mix internal phosphatide.
Physiological function
A large number of sheep, miniature pig and result of study of the chicken propose, arsenic is the essential microelement. While including lower arsenic in the beverage ' 10- 30mg/g) ,Result in, grow stagnat reason, pregnant to reduce, miscarry spontaneously more, mortality is relatively high. The skeleton ore is lowered, also observe withering in sheep and miniature pig to cardiac muscle and skeleton muscle fibre, the mitochondrial membrane can break to change. Arsenic has not been confirmed in the internal biochemical function yet, but may work to brief to study on arsenic in some enzymes react, substitute phosphate as activator of enzyme with arsenic sour salt, react with sulfhydryl- base as enzyme inhibitor in the form of inferior arsenic sour salt, thus can obviously influence the activity of some enzymes. Someone observe, make the intersection of patient and their blood arsenic content that blood dialyse, reduce, and might relate to patient's centre nerve problems, vascular disease.
Physical needs
Propose, people's arsenic requirement is 6.25 g/4.18MJ- 12.5 g/4.18MJ, the intaking amount of arsenic from all parts of the world is generally 12- 40 g according to animal's experiment materials, take in the intersection of marine product and many person, intaking amount of arsenic can reach every day 195 g.
Excessive to behave
The disposition of arsenic relates to compound, inorganic arsenic oxide and oxyacid are reasons of the most common arsenic poisoning. Find that can confirm whether are poisoned through arsenic of the urine, the tentative standard is that arsenic content of the urine reaches above 0.09mg/L in order to be poisoned. Can understand arsenic poisoning situation to take place arsenic too while finding, is poisoned the tentative standard and reached above 0.06 g/g in order to be poisoned in order to send arsenic content. But is influenced by environmental pollution, there should be standard of sending arsenic normal content of this area in every area.
Arsenic deficiency disease
In chick, hamster, goat, pig and mouse's experiment of coming out, it is that growth inhibiting and reproduction is unusual that arsenic lacks the most unanimous manifestation, the characteristic of the latter is fertilized ability and damaged and enclosed the increase of perinatal mortality. All species demonstrate the change of mineral content in various organs while lacking the arsenic. Reflect to some responses that arsenic lack that depend on that should surge the existence of factor or other factors.


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